Thermogravimetric Analysis
Determination of thermal stability and composition through mass variation.
O que é TGA
Uma técnica de análise avançada
Determination of thermal stability and composition through mass variation.
What sets us apart
We don't hand over a spectrum. We hand over the interpretation.
Any lab can return peaks and numbers. Our report reads the data. Three differences define what we deliver — illustrated below with a real, anonymized case.
Multiple techniques, one integrated report
We don't hand back five loose reports. We cross-reference every technique's results into a single reading — each signal checked against the others — to reach an answer, not a pile of data.
- Contamination investigation — identifying and tracing the source of a foreign species.
- Performance degradation — explaining why a batch behaves outside expectations.
- New supplier validation — proving equivalence before switching.
3 LDPE batches · 4 techniques converge, NMR reveals the difference
In semicrystalline polymer systems, thermomechanical processing variables influence chain conformational dynamics¹. Solid-state NMR resolves chemical environments at the nanometer scale², sensitive to changes not detectable by XRD or FTIR³.
Technical justification anchored in the literature
Every technique choice and every inference in the report is backed by peer-reviewed literature — with citations in the text. The conclusion isn't loose opinion: it's a traceable argument, defensible in an audit and in front of the client.
- Numbered citations linking claim to source
- Official standards and methods referenced per analyte
- Auditable reasoning end to end
Conclusion and expert opinion
The report closes with a clear position, signed by the Principal Investigator: what the data shows, what can't yet be claimed, and the next step. It includes an honest caveat on the limits of inference — what separates a technical opinion from a guess.
- Explicit technical position, not just results
- Inference limits declared honestly
- Next-step recommendation signed by the P.I.
Four techniques confirmed equivalence; only the solid-state NMR revealed the subtle conformational change not distinguishable by conventional QC — a molecular signature consistent with the atypical filtration behavior.
Without the industrial line's parameters, no direct causal correlation can be established — a complementary step is recommended for elucidation.
Aplicações de mercado
Onde a TGA entrega resultados
Market Applications
Pharma
- Residual moisture determination
- API thermal stability analysis
- Residual solvent quantification
- Thermal decomposition studies
- Mass loss analysis
Materials
- Polymer stability characterization
- Composite filler determination
- Volatile additive analysis
- Thermal degradation studies
- Ash quantification
Cosmetics
- Water content determination
- Product stability analysis
- Volatile quantification
- Preservation studies
- Natural product analysis
FAQ
Frequently Asked Questions about Thermogravimetric Analysis (TGA)
What is derivative TGA (DTG) and what does it add to a standard TGA curve?
- DTG is the mathematical derivative of the TGA mass-loss curve with respect to temperature or time, converting gradual mass-loss steps into distinct peaks. It makes it much easier to identify the exact temperature of each decomposition or mass-loss event and to separate overlapping steps that are hard to distinguish on the raw TGA curve alone.
How much sample is needed for a TGA measurement?
- TGA typically requires only a small amount of sample — often just a few milligrams — since the technique measures a relative mass change (percentage) rather than an absolute quantity, though enough material is needed to ensure the sample is representative of the bulk material.
Does the atmosphere (nitrogen vs. air) used during TGA matter?
- Yes — running TGA under an inert atmosphere (such as nitrogen) isolates purely thermal decomposition and volatilization, while running under air or oxygen introduces oxidative degradation, which can occur at different temperatures and produce different mass-loss behavior. The appropriate atmosphere depends on what the analysis is trying to characterize.
Can TGA distinguish between multiple overlapping decomposition steps?
- TGA can resolve mass-loss events that occur at sufficiently different temperatures, and the derivative (DTG) curve helps separate steps that appear as a single gradual slope on the raw TGA trace — though steps that occur very close in temperature can still be difficult to fully resolve and may require a slower heating rate or complementary technique.
Can TGA be used to estimate a material's composition?
- Yes, when a sample's components decompose or lose mass at sufficiently distinct temperatures — for example, moisture loss, then a specific additive's decomposition, then polymer degradation, then residual ash — the mass lost at each stage provides an approximate compositional breakdown of the sample.
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