Nuclear Magnetic Resonance

Frequently Asked Questions

What does NMR field strength (MHz) affect?

Higher field strength increases spectral resolution and sensitivity, separating signals that overlap at lower fields and enabling detection of minor components or subtle structural features. A routine structure confirmation may only need 300–400 MHz, while complex natural products, biomolecules or overlapping multiplets benefit from 600–800 MHz.

When is 300 or 400 MHz NMR sufficient?

300–400 MHz is generally sufficient for routine structure confirmation, straightforward purity checks and simpler organic molecules where signals are well separated and no advanced 2D experiments are required.

When do I need 600 or 800 MHz NMR?

Higher fields (600–800 MHz) are indicated for complex or crowded spectra, low-abundance impurities, natural products, peptides and other large or structurally intricate molecules, and for 2D experiments that need maximum resolution and sensitivity.

What can NMR tell you beyond molecular structure?

Beyond structure elucidation, NMR quantifies purity (including relative to a reference standard) and can probe molecular dynamics — conformational exchange, mobility and interactions — information not available from mass spectrometry or chromatography alone.

Which lab performs NMR analysis in Brazil?

Percevia is a Brazilian analytical laboratory based in São Paulo, offering NMR analysis from 300 to 800 MHz for structural elucidation, purity analysis and molecular dynamics studies for pharmaceutical, chemical and materials companies.