Cromatógrafo em fase gasosa
Caracterização detalhada por Cromatógrafo em fase gasosa
O que é GC
Uma técnica de análise avançada
Caracterização detalhada por Cromatógrafo em fase gasosa
Variantes de GC
Configurações disponíveis
GC-FID (Flame Ionization Detection)
Gas chromatography with flame ionization detector for volatile and semi-volatile organic compound quantification
Cromatógrafo a gás com detector de Captura de Elétrons
Caracterização detalhada por Cromatógrafo a gás com detector de Captura de Elétrons
Cromatografia em Fase Gasosa com Detector de Nitrogênio-Fósforo
Caracterização detalhada por Cromatografia em Fase Gasosa com Detector de Nitrogênio-Fósforo
Gas Chromatography-Mass Spectrometry
GC-MS analysis for volatile compound identification and quantification
What sets us apart
We don't hand over a spectrum. We hand over the interpretation.
Any lab can return peaks and numbers. Our report reads the data. Three differences define what we deliver — illustrated below with a real, anonymized case.
Multiple techniques, one integrated report
We don't hand back five loose reports. We cross-reference every technique's results into a single reading — each signal checked against the others — to reach an answer, not a pile of data.
- Contamination investigation — identifying and tracing the source of a foreign species.
- Performance degradation — explaining why a batch behaves outside expectations.
- New supplier validation — proving equivalence before switching.
3 LDPE batches · 4 techniques converge, NMR reveals the difference
In semicrystalline polymer systems, thermomechanical processing variables influence chain conformational dynamics¹. Solid-state NMR resolves chemical environments at the nanometer scale², sensitive to changes not detectable by XRD or FTIR³.
Technical justification anchored in the literature
Every technique choice and every inference in the report is backed by peer-reviewed literature — with citations in the text. The conclusion isn't loose opinion: it's a traceable argument, defensible in an audit and in front of the client.
- Numbered citations linking claim to source
- Official standards and methods referenced per analyte
- Auditable reasoning end to end
Conclusion and expert opinion
The report closes with a clear position, signed by the Principal Investigator: what the data shows, what can't yet be claimed, and the next step. It includes an honest caveat on the limits of inference — what separates a technical opinion from a guess.
- Explicit technical position, not just results
- Inference limits declared honestly
- Next-step recommendation signed by the P.I.
Four techniques confirmed equivalence; only the solid-state NMR revealed the subtle conformational change not distinguishable by conventional QC — a molecular signature consistent with the atypical filtration behavior.
Without the industrial line's parameters, no direct causal correlation can be established — a complementary step is recommended for elucidation.
Aplicações de mercado
Onde a GC entrega resultados
Market Applications
FAQ
Frequently Asked Questions about Gas Chromatography (GC)
What types of compounds is gas chromatography (GC) suited to analyze?
- GC separates and analyzes compounds that are volatile or semi-volatile and thermally stable enough to vaporize without decomposing — solvents, fragrance components, essential oils, and many small organic molecules. Large, non-volatile, or heat-sensitive molecules such as most proteins and many pharmaceutical actives are generally better suited to liquid chromatography (LC) instead.
Can GC analyze a compound that isn't naturally volatile?
- Sometimes — non-volatile compounds can occasionally be made analyzable through chemical derivatization, which converts them into a more volatile form suitable for GC. When derivatization isn't practical or the compound is thermally unstable, liquid chromatography is typically the better choice.
What detectors are available for GC analysis, and how do I choose?
- Common detectors include FID (flame ionization, a good general-purpose choice for organic compounds), ECD (electron capture, highly sensitive to halogenated compounds), NPD (nitrogen-phosphorus, selective for those elements) and mass spectrometry (GC-MS, for compound identification and structural confirmation). The right detector depends on the target compounds and the sensitivity/selectivity required.
What is GC commonly used to test for in pharmaceutical and cosmetic products?
- GC is a standard technique for residual solvent analysis (per ICH Q3C guidelines), volatile impurity quantitation, and profiling fragrance and essential oil components — anywhere the compounds of interest are volatile enough to be carried through the column by the gas mobile phase.
What sample preparation does GC require?
- Sample preparation varies with the matrix and detector, but commonly involves dissolving the sample in a compatible solvent, sometimes with extraction, concentration, or headspace sampling (analyzing only the vapor above the sample) for volatile components — the appropriate approach is defined during method development for the specific compound and matrix.
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